Miaoli District Agricultural Research and Extension Station was started on March 25, 1998 under the supervision of the Taiwan Provincial Department of Agriculture and Forestry. It was later placed under the Council of Agriculture, Executive Yuan of the Central Government, as a result of the simplification of Taiwan Provincial Administration on July 1, 1999. On August 1, 2023, it was organized for adjustment in response to administrative agencies as Miaoli District Agricultural Research and Extension Station, Ministry of Agriculture (MDARES, MOA). History of the name of this Station is summarized as follows:

The Station was previously called Sericulture Improvement Station which was originally established as Mulberry Propagation Unit at Gong-Guan, Taipei City, by Japanese Viceroy Administration in 1910. After Taiwan was restored from the Japanese occupation, this unit was merged into the Silkworm Rearing Unit of the Department of Agriculture and Forestry, and renamed are the Taiwan Provincial Sericulture Experiment Station in 1949. In 1977 as a result of city development, the Station was moved from Taipei City to Miaoli County. In 1992, the Station was renamed are Sericulture and Apiculture Experiment Station to cover the researches on silkworm and honeybee. In 1997, this Station was further reorganized as Miaoli District Agricultural Research and Extension Station under Taiwan Provincial Department of Agriculture and Forestry (1998~1999), Council of Agriculture (1999~2023), and Ministry of Agriculture (2023~ ) so that to expand the scope of research activities to include food and horticultural crops while retaining the unique fields of silkworm and honeybee which are not included in other six Agricultural Research and Extension Stations in Taiwan.